sales@fnfresearch.comTel: +91 96043 17127 | USA: 1 (347) 690-0211

Home / All latest News / Global B-Cell Maturation Antigen (BCMA) Targeted Therapies Market

Global B-Cell Maturation Antigen (BCMA) Targeted Therapies Market Projected to Reach USD 16,487.4 Million by 2026

29-Apr-2021 | Facts and Factors

As per the report published by Facts and Factors, the global B-Cell Maturation Antigen (BCMA) Targeted Therapies Market was valued at approximately USD 5,150.4 Million in 2020 and is expected to generate revenue of around USD 16,487.4 Million by end of 2026, growing at a CAGR of around 21.4% between 2021 and 2026.

Targeted therapy for B-cell maturation antigen (BCMA) (BCMA-TT) has emerged as a potential treatment for Multiple Myeloma (MM). bispecific antibody constructs, Antibody-drug conjugates (ADCs), containing chimeric antigen receptor (CAR)-modified T-cell therapy, BiTE (bispecific T-cell engager) immuno-oncology therapies, and are the three most popular treatment modalities for targeting BCMA.

Request Sample Request Customization Buy Now

Blenrep, a GSK antibody-drug conjugate, was the first FDA-approved anti-BCMA treatment for highly refractory Multiple Myeloma in August 2020. (MM). The FDA has now approved a second drug that targets this antigen.

The cell surface protein BCMA is expressed on malignant plasma cells. In patients with multiple myeloma, expression profiles of BAFF-R and TACI are lower than those of B-Cell maturation antigen. Furthermore, these antigens are rarely found in malignant plasma cells, implying that B-Cell maturation antigen is a preferred targeting antigen over others. With progression from usual Monoclonal Gammopathy of Undetermined Significance to smoldering many myeloma (SMM) to active numerous myeloma, the expression of BCMA steadily increases. Since B-Cell maturation antigen cells have a very limited expression pattern and are not expressed in regular human tissues, they have a special expression profile. As a result, B-Cell maturation antigen -target therapy has gained traction in cancer care and will be the treatment of choice, especially for multiple myeloma. Myeloma cell survival is regulated by BCMA's co-immunoprecipitation property with the master transcription factor (IRF-4). Based on product class, B-Cell maturation antigen targeted therapies actively include three main forms of immunotherapies: CAR T Cells, antibody-drug conjugates, and bispecific antibodies.

Multiple myeloma (MM) is a clonal plasma cell malignant neoplasm that develops in the bone marrow's soft, spongy tissue. Plasma cells are an important component of the immune system that aids in the battle against infections and other diseases. Low blood counts, renal dysfunction, hypercalcemia, immune suppression, monoclonal gammopathy, and anemia are all symptoms of multiple myeloma, cancer caused by malignant plasma cells. In addition, multiple myeloma is also an incurable condition. According to the American Cancer Society, an estimated 30,280 adults (17,490 men and 12,790 women) will be diagnosed with multiple myeloma in the United States in 2017, with 12,590 deaths (6,660 men and 5,930 women) due to the disease. Multiple myeloma accounts for 8.2% of all blood cancers in Africa, according to the National Center for Biotechnology Information.

Top Market Players

Major players in the B-Cell Maturation Antigen (BCMA) targeted therapies market are Sutro Biopharma, Malin Corporation, Eureka Therapeutics, Transposagen Biopharmaceuticals, firstVentury Equity, Five Prime Therapeutics, Bluebird Bio, Dana-Farber Cancer Institute, Deerfield Partners, Onyx Pharmaceuticals, GlaxoSmithKline plc, Novartis AG, Gilead Sciences. Inc., Amgen Inc., Affimed N.V, Autolus Ltd., Juno Therapeutics, Celgene Corporation, and Poseida Therapeutics, Inc., amongst others.

Growing Investment by Market Players

Players in the market are investing heavily in the research and production of new multiple myeloma therapies. Chimeric antigen receptor T cells, antibody-drug conjugates, and Bi-specific antibodies are examples of these therapies. GlaxoSmithKline Plc. (GSK2857916), for example, is working on an antibody-drug conjugate for relapsed/refractory multiple myeloma and other advanced hematologic malignancies that express BCMA. The demand for B-cell maturation Antigen (BCMA) targeted therapies is expected to develop due to a strong pipeline of therapies for the treatment of multiple myeloma.

Chemotherapy and radiation therapy patients are at a high risk of cancer recurrence when they gain resistance to these treatments. There are currently no treatment options for patients with recurrent cancer, so the BCMA targeted therapies represent a significant advancement in the treatment of relapsed or refractory multiple myeloma, where conventional treatment modalities have proven to be ineffective.

North America is projected to Dominate Global B-Cell Maturation Antigen (BCMA) Targeted Therapies Market Growth

North America led the global B-Cell Maturation Antigen (BCMA) targeted therapies market in 2020. The United States held the majority share in North America -Cell Maturation Antigen (BCMA) targeted therapies market owing to ongoing development in the region paired with the presence of key market players. The Asia Pacific is expected to the fastest-growing region for the global B-Cell Maturation Antigen (BCMA) targeted therapies market owing to increasing demand in China, and India.

Browse the full “B-Cell Maturation Antigen (BCMA) Targeted Therapies Market by Product Type (CAR-T cell, Antibody Drug Conjugates and Bispecific Antibodies), By Indication (Multiple Myeloma and Acute Lymphoblastic Leukemia) By End User (Hospitals and Cancer Research Institute) By Region: Global Industry Perspective, Comprehensive Analysis, and Forecast, 2020 – 2026” report at https://www.fnfresearch.com/global-b-cell-maturation-antigen-bcma-targeted-therapies-market.

The Global B-Cell Maturation Antigen (BCMA) targeted therapies market is segmented as follows:

By Product Type:

  • CAR-T Cell
  • Antibody Drug Conjugates
  • Bispecific Antibodies

By Indication:

  • Multiple Myeloma
  • Acute Lymphoblastic Leukemia

By End User:

  • Hospitals
  • Cancer Research Institute


By Region:

  • North America
    • The U.S.
    • Canada
  • Europe
    • France
    • The UK
    • Spain
    • Germany
    • Italy
    • Rest of Europe
  • Asia Pacific
    • China
    • Japan
    • India
    • South Korea
    • Southeast Asia
    • Rest of Asia Pacific
  • Latin America
    • Brazil
    • Mexico
    • Rest of Latin America
  • Middle East & Africa
    • GCC Countries
    • South Africa
    • Rest of Middle East & Africa

About Us:

Facts & Factors is a leading market research organization offering industry expertise and scrupulous consulting services to clients for their business development. The reports and services offered by Facts and Factors are used by prestigious academic institutions, start-ups, and companies globally to measure and understand the changing international and regional business backgrounds. Our client’s/customer’s conviction on our solutions and services has pushed us in delivering always the best. Our advanced research solutions have helped them in appropriate decision-making and guidance for strategies to expand their business.

Contact Us:
Facts & Factors

A 2108, Sargam,
Nanded City,
Sinhagad Road,
Pune 411041, India
USA: +1 (347) 690-0211
Email: sales@fnfresearch.com
Web: https://www.fnfresearch.com

Latest Added Market Report

B2C Mobility Sharing Market By Service Model (Car Sharing, Bike Sharing, Scooter Sharing, Ride Hailing And Others) By Vehicle Type (Cars, Two Wheelers, And Others), By Region: Global Industry Perspective, Comprehensive Analysis, and Forecast, 2021 – 2026

[228+ Pages Report] According to a Facts and Factors report, the global B2C Mobility Sharing market is estimated to be around USD 35 Billion in 2020, with annual sales of approximately USD 99 Billion at the end of 2026, representing a CAGR of around 30% from 2021 to 2026. Global B2C Mobility Sharing Market: Overview&n ...

Published Date : 30-Apr-2021 | | Category : Technology & Media | Pages : 228 | Format : Read more

Vehicle Roadside Assistance Market by Service (Towing, Fuel Delivery, Jump Start/Pull Start, Lockout/ Replacement Key Services, Battery Assistance, Trip Routing/ Navigational Assistance, Winch, Tire Replacement, and Other Mechanic Services), Providers (Motor Insurance, Independent Warranty, Auto Manufacturer, Automotive Clubs), and by Vehicle Type (Commercial Vehicle, Passenger Vehicle): U.S. and Canada Industry Perspective, Comprehensive Analysis, and Forecast, 2020 – 2026

[193+ Pages Report] According to a Facts and Factors market research study, the Vehicle Roadside Assistance market in the United States and Canada was registered at around USD 5,300.0 million in 2020, and is forecast to produce revenues worth around USD 6,232 million by the end of 2026, rising at a CAGR of around 3.66 percent between 2021 and 2026. U.S. and Canada Vehicle Roadside ...

Published Date : 30-Apr-2021 | | Category : Automotive | Pages : 193 | Format : Read more

Learning Experience Platform (LXP) Market By Learning Type (Self-Paced, Instructor-Led and Others), By Deployment Mode (Cloud-based and On-premises), By Enterprise Size (Large Enterprise, and Small & Medium Enterprise), and By End-user (Academic, and Corporate): Global Industry Perspective, Comprehensive Analysis, and Forecast, 2020 – 2026

[197+ Pages Report] As per the latest research and survey report issued by Facts and Factors, the globallearning experience platform (LXP or LEP) market was valued at around 508.5 million in 2020 which was around USD 350 million in 2019 and is expected to register revenues worth 2,186.4 million by the end of 2026, growing at an exceptional CAGR of approximately 25.3 percent between 2021 and 2 ...

Published Date : 30-Apr-2021 | | Category : Technology & Media | Pages : 197 | Format : Read more

Facts & Factors provides an array of marketing and business research solutions distinctly designed by our expertise for the clients.
Copyright © 2021 Facts & Factors. All Rights Reserved. Sitemap - Privacy Policy - Terms & Conditions